UnknownNot Applicable

Evaluation of High Velocity Nasal Insufflation in Management of Respiratory Failure in Patients With Overlap Syndrome

Egypt50 participantsStarted 2023-03

Plain-language summary

High velocity nasal insufflation (HVNI), a form of HFNC that utilizes a small bore nasal cannula to generate higher velocities of gas delivery than HFNC which uses large bore cannula, has the ability to accomplish complete purge of extra thoracic dead space at flow rates of 35 litres/min and may be able to provide ventilatory support in patients with respiratory failure in addition to oxygenation support in patients with overlap syndrome. This study aims to evaluate the effectiveness of HVNI compared to NIMV in management of respiratory failure in patients with obesity hypoventilation syndrome and overlap syndrome.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with respiratory failure in obesity hypoventilation syndrome and overlap syndrome, requiring ICU admission and fulfill criteria of NIMV supplementation (GOLD criteria 2021) * patients with obesity hypoventilation syndrome and overlap syndrome diagnosed by polysomnogram or through STOP BANG Questionnaire or EPWORTH Sleepness Scale. Exclusion Criteria: * Patients less than 18 years old * Patients with hemodynamic instability * Patients with central causes of hypercapnic respiratory failure * Patients with disturbed conscious level * Patients who refuse to participate in the study

What they're measuring

Evaluation of HVNI in correction of Acidosis .

Timeframe: Baseline

Evaluation of HVNI in correction of Hypercapnia.

Timeframe: Baseline

Trial details

NCT IDNCT05190458

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03

Contact for this trial

Abanoub H Sadek Farag, Resident

+201279269591 Abanoubabanoubhanysadek@outlook.com