CompletedNot Applicable

Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid

Italy22 participantsStarted 2022-01-12

Plain-language summary

The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of a hyaluronic acid-based gel, compared to MINSD alone. A total of 22 patients will be enrolled, selected by inclusion and exclusion criteria and randomly divided in two groups: hyaluronic acid group (HA) and no-hyaluronic acid group (No-HA).

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients diagnosed with periodontitis; * Age ≥ 18 years old; * Presence of at least 10 teeth per arch; * Presence of at least two teeth with Probing Depth (PD) ≥ 5 mm per quadrant; * Presence of at least one intraosseous pocket; * Single-rooted and multi-rooted teeth. Exclusion Criteria: * Patients with systemic diseases; * Prolonged antibiotic or anti-inflammatory treatment within 4 weeks prior to periodontal therapy; * Pregnant or lactating; * Tobacco smokers (≥ 10 cigarettes per day); * Multi-rooted teeth with furcation involvement; * Third molars.

What they're measuring

Change of Probing Depth (PD) (millimeters)

Timeframe: baseline and 6 months after periodontal therapy

Trial details

NCT IDNCT05188898

SponsorFederico II University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-08

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