UnknownNot Applicable

Hemodynamics and Myocardial Injury After Non-cardiac Surgery

Canada750 participantsStarted 2022-01-01

Plain-language summary

The incidence of myocardial injury after non-cardiac surgery (MINS) is approximately 12-15% and is associated with an increased risk of 30-day mortality, 1-year mortality, and 2-year major vascular events. Using both traditional longitudinal analysis techniques and novel methods in machine learning, investigators will explore whether intraoperative and postoperative vital signs can enhance MINS surveillance by providing temporal prediction of MINS events.

Who can participate

Age range45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who underwent inpatient noncardiac surgery, who had myocardial injury after non-cardiac surgery (MINS) protocol ordered for postoperative high sensitivity troponin monitoring based on the Canadian Cardiovascular Society (CCS) guidelines * Patients who underwent inpatient non-cardiac surgery from January 2020 to June 2021. Exclusion Criteria: * Patients who did not have intraoperative and postoperative vital signs * Patients who did not have any postoperative troponin measurements * Patients who underwent repeat surgery * Patients who were readmitted within the first 72 hours postoperatively * Patients who had positive troponin on postoperative day 4

What they're measuring

High Sensitivity Troponin (hsTnT) levels (daily)

Timeframe: Up to and including postoperative day 2

Trial details

NCT IDNCT05188001

SponsorUniversity of British Columbia

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-31

View on ClinicalTrials.gov More Myocardial Injury trials