Active Gains in Brain Using Exercise During Aging (NCT05186090) | Clinical Trial Compass
CompletedNot Applicable
Active Gains in Brain Using Exercise During Aging
Spain90 participantsStarted 2021-01-02
Plain-language summary
AGUEDA (Active Gains in brain using Exercise During Aging) is a randomized controlled trial designed to examine the effects of a 24-week resistance exercise program on brain health in cognitively normal adults between 65-80 years of age.
Who can participate
Age range65 Years – 80 Years
SexALL
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Inclusion Criteria:
* Men and women 65 - 80 years.
* Able to speak and read fluent Spanish.
* Living in community during the study.
* Reliable means of transportation.
* Being physical inactive (i.e., not to be participating in the last 6 months in any resistance exercise program, or accumulating less than 600 METS/Week of moderate-vigorous physical activity).
* Classified as cognitively normal according to Stics-m MMSE and MOCA tests.
Exclusion Criteria:
* Ambulatory with pain or regular use of an assisted walking device.
* Medical contraindication for inclusion in an exercise program.
* Neurological condition (Multiple Sclerosis, Parkinson Disease, Dementia) or brain injury (traumatic or stroke).
* Current diagnosis and treatment of a DSM-V Axis I or II disorder including major depression and seeing a psychologist, therapist, or psychiatrist.
* History of major psychiatric illness including schizophrenia, general anxiety disorder or depression (GDS-30\>=15).
* Current treatment for congestive heart failure, angina, uncontrolled arrhythmia, deep venous thrombosis or other cardiovascular event.
* Myocardial infarction, coronary artery bypass grafting, angioplasty or other cardiac condition in the past year.
* Current or previous treatment for any type of cancer.
* Type I Diabetes or uncontrolled Type II Diabetes defined as Insulin dependent or Hba1C greater than 10.
* Recent treatment for alcohol or substance abuse.
* Presence of metal implants (e.g., pacemaker, stents, jo…