UnknownNot Applicable

The Effect of Dietary Intervention on Endothelial Glycocalyx in Psoriasis

Greece60 participantsStarted 2022-11-01

Plain-language summary

The food supplement Endocalyx is considered to support the endothelial glycocalyx integrity by supplying sulfated polysaccharides, anti-oxidant enzymes and additional substrates for glycocalyx synthesis. The investigators will study the effect of Endocalyx on endothelial, vascular and left ventricular myocardial function in patients with psoriatic disease.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Caucasian patients with psoriatic disease (plaque-type psoriasis or psoriatic arthritis) * Body mass index ≥18.5 Kg/m2 * If female, patients must be non-pregnant and non-breastfeeding Exclusion Criteria: * History of acute coronary syndrome. Coronary artery disease will be excluded by a clinical history, examination and electrocardiogram. * Moderate or severe valve disease * Primary cardiomyopathies * Chronic obstructive pulmonary disease * Asthma * Chronic kidney disease * Liver failure * Malignancies

What they're measuring

Endocalyx effects on endothelial glycocalyx thickness

Timeframe: four months

Trial details

NCT IDNCT05184699

SponsorUniversity of Athens

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-11-01

Contact for this trial

Ignatios Ikonomidis, Professor

+302105832187 ignoik@gmail.com

View on ClinicalTrials.gov More Psoriasis trials