CompletedNot Applicable

Effects of BIS Closed Loop Target Controlled Infusion on Perioperative Inflammatory Response and Prognosis of Elderly Patients Undergoing Laparoscopic Radical Gastrectomy for Gastric Cancer

China73 participantsStarted 2018-01-01

Plain-language summary

The purpose of this study is to find the elderly patients with laparoscopic gastric cancer radical is suitable the BIS closed round target control level of anesthesia depth of sedation, can decrease the elderly laparoscopic gastric cancer radical surgery in patients with perioperative inflammatory reaction, and reduce the incidence of perioperative pulmonary complications such as, for elderly patients with gastric cancer radical perioperative inflammation control to provide the reference and provide guidance for clinical anesthesia work.

Who can participate

Age range65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Age 65 or above ASA-PSTYPE I or II Both male and female Laparoscopic radical gastrectomy for gastric cancer Exclusion Criteria: The patient had abnormal liver, kidney and other important organs before surgery The patient has chronic pain Patients with neurological or mental disorders Long-term use of sedation, painkillers and antipsychotic drugs The patient has contraindications for opioid use

What they're measuring

Postoperative complications

Timeframe: Within one week after surgery

mortality rate

Timeframe: Within 30 days after surgery

Serum LEVELS of IL-2, IL-4, IL-6, IL-10, TNF-ɑ, IFN-γ

Timeframe: Within three days of the surgery

Trial details

NCT IDNCT05173909

SponsorZhonghua Chen,MD

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12-01

View on ClinicalTrials.gov More The Effect of BIS Closed-loop Target Control on Postoperative Operation trials