The objective of this randomized control trial is to determine the effectiveness of myofascial release in patients with nonspecific low back pain to improve Pain, Disability, and Quality of life This study is being conducted at the Outpatient Physiotherapy department of Sindh Institute of Physical Medicine and Rehabilitation, Karachi (former institute of Dow University of Health Sciences) and Musculoskeletal outpatient department of Dr. Ruth K. M. Pfau, Civil Hospital Karachi among 72 patients with nonspecific back pain on the basis of non-probability purposive sample technique with screening for study criteria through a consultant physician (blinded). After taking informed consent, all participants will be randomly allocated into two groups through a second researcher who is not involved in screening, baseline assessment, and providing intervention. Group 1 will receive myofascial release with generalized low back stretching and thermotherapy and Group 2 will receive Posterior-anterior glide with generalized low back stretching and thermotherapy. A total of 18 sessions will be provided. Outcomes will be assessed at baseline, at the last session, and after 12 weeks of follow-up.
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change from baseline in pain on Short Form McGill Questionnaire 2 (SFMPQ-2) at 6 weeks (post intervention).
Timeframe: Baseline and Post Intervention
Change from baseline in pain on Short Form McGill Questionnaire 2 (SFMPQ-2) at 12 weeks follow-up.
Timeframe: Baseline and 12 weeks follow-up
Change from 6 weeks (post intervention) in pain on Short Form McGill Questionnaire 2 (SFMPQ-2) at 12 weeks follow-up.
Timeframe: Post Intervention and 12 weeks follow-up
Change from baseline in disability on the Roland Morris Disability Questionnaire at 6 weeks (post intervention)..
Timeframe: Baseline and Post Intervention
Change from baseline in disability on the Roland Morris Disability Questionnaire at 12 weeks follow-up.
Timeframe: Baseline and 12 weeks follow-up
Change from 6 weeks (post intervention) in disability on the Roland Morris Disability Questionnaire at 12 weeks follow-up.
Timeframe: Post Intervention and 12 weeks follow-up
Change from baseline in Quality of life on the WHOQOL BREF at 6 weeks (post intervention).
Timeframe: Baseline and Post Intervention
Change from baseline in Quality of life on the WHOQOL BREF at 12 weeks follow-up.
Timeframe: Baseline and 12 weeks follow-up
Change from 6 weeks (post intervention) in Quality of life on the WHOQOL BREF at 12 weeks follow-up.
Timeframe: Post Intervention and 12 weeks follow-up