CompletedNot Applicable

Letrozole /GnRH Antagonist Protocol in Women Over 40 Years Undergoing ICSI Cycle

Egypt200 participantsStarted 2021-11-01

Plain-language summary

The aim of this study To compare the clinical and laboratory outcomes of two ovarian stimulation protocols (standard GnRH antagonist protocol and aromatase inhibitor/ antagonist protocol) in women (40-44) years undergoing ICSI cycle.

Who can participate

Age range40 Years – 44 Years

SexFEMALE

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Inclusion Criteria: * Women between 40- 44-years undergoing ICSI cycle with FSH less than 15 and AMH more than 0.30. Exclusion Criteria: * Azoospermia in male partner, * Previous ovarian surgery, * Severe endometriosis, * Uterine cavity lesion * Metabolic or endocrine disorders including hyperprolactinemia and ypo/hyperthyroidism. * Previous failed ICSI cycle. * BMI more than 30.

What they're measuring

live birth rate

Timeframe: 1 year after embryo transfer

Trial details

NCT IDNCT05166668

SponsorMenoufia University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-10

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