CompletedNot Applicable

Reproductive Outcome After Sperm Selection for Intracytoplasmic Sperm Injection (ICSI) Using Zona Pellucida Proteins

Bulgaria368 participantsStarted 2021-12-03

Plain-language summary

The aim of this study is to analyze the effect of a sperm selection method by adhesion to partners' zona pellucida proteins on the assisted reproduction treatment (ART) outcome parameters.

Who can participate

Age range20 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinical diagnosis for primary or secondary infertility * Healthy females * Clinical diagnosis for unexplained infertility * Females between 20 and 45 years old. * Males between 20 and 50 years old. * At least 3 retrieved oocytes per follicular puncture with at least 1 oocyte at germinal vesicle (GV) or metaphase I (MI) stage Exclusion Criteria: * Presence of low quality oocytes * Females with endometrial or ovarian infertility factor

What they're measuring

Fertilisation rate

Timeframe: 24 hours after ICSI

Embryo quality

Timeframe: 2 to 6 days after ICSI

Implantation rate

Timeframe: 14 days after embryo transfer

Clinical pregnancy rate

Timeframe: 6 weeks after embryo transfer

Trial details

NCT IDNCT05161247

SponsorNadezhda Women's Health Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-03

View on ClinicalTrials.gov More Infertility, Male trials