In this parallel, multicenter, single-blind randomized controlled trial, mechanical ventilated patients will be randomly assigned to two groups. One receives remimazolam to achieve sedation goals, while the other receives Midazolam. The primary outcome is the effect of remimazolam on duration of mechanical ventilated of critical patients compared to midazolam.
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Duration of mechanical ventilation
Timeframe: From the date of enrollment until the date of successful ventilator withdrawal, assessed up to 28 days