Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry (NCT05158751) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry
United States100 participantsStarted 2026-01
Plain-language summary
To assess potential link between unrecognized myocardial inflammation (myocarditis) and premature ventricular contractions (PVCs) associated with and without reduced Left ventricular ejection fraction (LVEF) through comprehensive diagnostic work up.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients \> 18 years of age with mono-morphic or polymorphic PVC burden of ≥5000 in 24 hours.
* Non-sustained VT was defined as ≥3 more consecutive beats lasting \<30 seconds
Exclusion Criteria:
* History of myocardial infarction,
* Significant flow-limiting coronary artery disease (≥50% stenosis) on invasive coronary angiography or CT angiography,
* History of revascularization,
* Significant symptomatic atrial arrhythmias associated with LV dysfunction,
* Severe valvular disease,
* Cardiomyopathy attributed to toxins such as alcohol and illicit drugs,
* History of cardiac arrest,
* History of channelopathies or inherited arrhythmias.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Identify the underlying myocarditis in patients presenting with PVCs with or without reduced LVEF
Timeframe: Retrospective Collection between dates January 2014-January 2023
Trial details
NCT IDNCT05158751
SponsorKansas City Heart Rhythm Research Foundation