TerminatedPhase 4

Outpatient Recovery From Acute Kidney Injury Requiring Dialysis

Stopped: Inadequate recruitment

United States1 participantsStarted 2021-10-18

Plain-language summary

There are currently no therapies to improve the chances of recovering enough kidney function to come off of dialysis after severe acute kidney injury. It is not known if current routine outpatient dialysis treatments are optimized to maximize the chances of recovery. The purpose of this pilot study is to see if we can feasibly and safely provide several changes to the way that dialysis is provided in outpatient dialysis centers which may improve the chances of recovery.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * AKI-D (acute kidney injury requiring dialysis), attributed at least in part to acute tubular necrosis by clinical nephrology team * Age ≥ 18 years * Pre-hospitalization eGFR ≥ 15 mL/min/1.73m2 * Being discharged to a participating outpatient dialysis unit (within 30 miles of UCSF) Exclusion Criteria: * Known loop diuretic allergy/intolerance * Dialysis duration \> 3 months * Pregnant * Prisoner * Unable to consent * Clinical team declines to allow approach for study

What they're measuring

The Proportion of Patients Who Received the Dialysate Temperature, Dialysate Sodium Concentration, Diuretic Dose, and Ultrafiltration Hold Threshold That Was Ordered at Least Once in the First Two Weeks of Treatment.

Timeframe: First two weeks of study intervention

Trial details

NCT IDNCT05158153

SponsorUniversity of California, San Francisco

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-04-19

Results submitted2023-04-18

View on ClinicalTrials.gov More Acute Kidney Injury trials