UnknownNot Applicable

Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia

140 participantsStarted 2022-01-01

Plain-language summary

The aim of this study is to investigate the impact of co-administration of Pentoxifylline and Zinc sulfate on oxidative stress, apoptosis, and inflammation, sperm capacitation and parameters in infertile men.

Who can participate

Age range20 Years – 50 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Idiopathic infertile men * have had at least one year of unprotected intercourse infertility * Sperm parameters abnormality Exclusion Criteria: * Men with varicocele * Hypersensitivity to pentoxifylline \& zinc, * pelvic organic pathologies * congenital adrenal hyperplasia * thyroid dysfunction * Cushing's syndrome * hyper prolactinemia * androgen secreting neoplasia * diabetes mellitus * consumption of medications affecting carbohydrate metabolism * severe hepatic * pancreatitis * kidney diseases * gallbladder diseases * Patients with alcohol consumption * Patients who use cigarettes and drugs