Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy

Inclusion Criteria: * Age 18-80 years; * Acute ischemic stroke caused by middle cerebral artery M1 segment occlusion; * Successful recanalization (mTICI 2b/3) after endovascular thrombectomy that confirmed by digital subtraction angiography; * Written informed consent provided by the patients or their legal relatives. Exclusion Criteria: * Known diagnosis or clinical suspicion of cerebral vasculitis or fibromuscular dysplasia; * Difficulty in reaching the designated position of the balloon used for ischemic post-conditioning; * Stenting in the middle cerebral artery as rescue therapy during the thrombectomy procedures; * \> 2 times of balloon dilations as rescue therapy due to angioplasty during the thrombectomy procedures; * Moderate or severe residual stenosis (≥ 50%) of the culprit artery after recanalization; * Difficulty in complying with ischemic post-conditioning or other conditions that the investigator considered inappropriate for inclusion.