UnknownNot Applicable

Diagnostic Value of sFlt-1/PlGF Ratio for the Etiology of Intra Uterine Growth Restriction - ANGIOPAG

France152 participantsStarted 2020-01-08

Plain-language summary

The main aim of this project is to determine the Placental Growth Factor and Vascular Endothelial Growth Factor ratio's performance (sFlt-1/PlGF) for the etiological diagnosis of vascular Intrauterine growth restriction (IUGR) compared to a non-vascular IUGR.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * \> 18 years old * Singleton pregnancy * Date of conception evaluated by ultrasound \< 14 WG * Consulting in one of the 3 participating centers for IUGR * Estimated fetal weight \< 5th centile (according to Hadlock 3 et CFEF) * Between 22+0 WG et 34+6 WG Exclusion Criteria: * Major birth defect diagnosed at time of inclusion * Abnormality of caryotype known at time of inclusion * Confirmed preeclampsia at time of inclusion

What they're measuring

To compare the PlGF / sFlt-1 ratio and placental lesions to confirm the diagnosis of vascular intrauterine growth retardation

Timeframe: 34+6 Weeks of Gestation

Trial details

NCT IDNCT05151289

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-29

Contact for this trial

Jeanne Sibiude, MD, PhD

01 40 60 66 11 jeanne.sibiude@aphp.fr

View on ClinicalTrials.gov More Intrauterine Growth Restriction trials