UnknownNot Applicable

The Effect of Micellized Food Supplements on Health-related Quality of Life in Patients With Post-acute COVID-19 Syndrome.

32 participantsStarted 2022-01-17

Plain-language summary

Food supplements like curcumin and boswellia serrata have been used traditionally for anti-inflammatory purposes. A well-known problem of these substances in their natural form is the low bioavailability. Micellization of these substances has been shown to increase the bioavailability significantly and thereby the clinical efficacy. The clinical value of these micellized substances has been presented in numerous clinical studies and in particular in patients with acute COVID-19. This study aims to examine the effect of a mixture of micellized curcumin, boswellia serrata and ascorbic acid on patients with long COVID.

Who can participate

Age range

18 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with confirmed SARS-CoV-2 infection at least 28 days prior to study participation * Patients who are experiencing symptoms of PACS (with a PCFS of 1 or higher) * 18 years or older and younger than 85 * Good understanding of written German Exclusion Criteria: * Currently under pharmacological treatment for PACS * Any planned medical surgery or intervention where medication intake is necessary in the coming 14 weeks * Allergy to curcumin or Boswellia * Active malignancy * Medical history of Human Immunodeficiency Virus (HIV) infection, or any serious immunocompromised state. * Pregnancy (or planned pregnancy in the coming 14 weeks) ( - Patients who are taking anticoagulants or have diabetes type I or II are only allowed to participate if their general practitioner is informed)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in health-related quality of life

Timeframe: Week 1, 2, 3, 4, 5, 6, 10 and 14.

Trial details

NCT IDNCT05150782

SponsorPhysioMetrics

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-10

Contact for this trial

Maurice de Graaf, MSc

+41 32 530 52 84 longcovid@physiometrics.ch

View on ClinicalTrials.gov More Post-acute COVID-19 Syndrome trials