Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic Appliances

Inclusion Criteria: * Fixed orthodontic patients aged 12-30 years old * Fixed orthodontic appliances on at least 1 arch (at least 10 teeth per arch) * Patients with good general health without any systemic diseases * Patients who are not using any herbal toothpaste or any mouthwash in daily life for the past 2 weeks * Patients who are not taking any medications which may influenced the pattern of oral ulceration * Patients who are willing and able to cooperate with all aspects of the protocol and able to communicate effectively and give informed written consent from parents if patients are younger than 18 years old Exclusion Criteria: * Cigarette smoking * History of hypersensitivity or allergy to turmeric or other ingredients of mouthwash * History of oral mucosal lesions and skin diseases * Oral ulceration or inflammation with unknown etiology * Pregnant or lactating women