Prospective Evaluation for Hybrid Cardiac Procedures

Inclusion Criteria: * Signed informed consent, inclusive of release of medical information * Age ≥ 18 years * CAD with indication for revascularization * Coronary anatomy as follows: * Multivessel-CAD involving the left anterior descending (LAD) (proximal or mid) and/or the left main (LM) (ostial, mid-shaft or distal) with at least one further epicardial coronary artery requiring treatment (LCX or RCA), OR * Single vessel disease involving the LAD and a major diagonal, both requiring independent revascularization with at least one stent * Severe aortic stenosis/insufficiency and/or mitral stenosis/insufficiency requiring surgery, with CAD (involving one or more vessels), suitable for PCI * CAD with indication for revascularization with severe unilateral carotid stenosis (\>85%) * Ability to tolerate, and no plans to interrupt dual antiplatelet therapy (DAPT) for: * At least 6 months in presentation was stable CAD, * At least 12 months if presentation was a biomarker-positive acute coronary syndrome (ACS) * Willing to comply with the follow-up required by the protocol. Exclusion Criteria: * Previous cardiac surgery of any kind * Previous thoracic surgery involving the left pleural space (if a left thoracotomy approach is planned) * Complicated or unsuccessful PCI within 30 days prior * Total occlusion (TIMI 0 or 1 flow) of the LM or LAD * Cardiogenic shock at time of screening * Any prior lung resection * End-stage renal disease on dialysis * Extra-cardiac illness…