TerminatedNot Applicable

Auricular Neurostimulation for Chemotherapy Induced Nausea and Vomiting

Stopped: Failure to accrue

United States18 participantsStarted 2021-04-29

Plain-language summary

This study evaluates the efficacy of auricular percutaneous electrical nerve field stimulator in children, adolescents and young adults with chemotherapy induced nausea and vomiting.

Who can participate

Age range

4 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subjects who are scheduled to be admitted for chemotherapy administration and who will have at least one additional cycle of the same chemotherapy * Chemotherapy regimens must include moderate and/or severe emetogenic chemotherapy Exclusion Criteria: * Significant developmental delays that would prohibit participation * Infection or severe dermatological condition of ear * Uncontrolled or severe infection * No implanted electrical device is permitted * Pregnancy * Severe cardiopulmonary disease * Diagnosis of hemophilia or other bleeding disorders * Diagnosis psoriasis vulgaris

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Baxter Retching Faces Scale

Timeframe: From the date of baseline assessment up to 7 days after completion of intervention ( day 13)

Change in Rhodes Index of Nausea, Vomiting and Retching (INVR)

Timeframe: From the date of baseline assessment and during the intervention (up to day 5)

Assessment of Rescue Medication

Timeframe: From the date of baseline assessment up to 7 days after completion of intervention ~ day 13

Trial details

NCT IDNCT05143554

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09-23

View on ClinicalTrials.gov More Chemotherapy-induced Nausea and Vomiting trials