Evaluation of the Effect of Repetitive Peripheral Magnetic Stimulation on Upper Extremity Spastic… (NCT05141695) | Clinical Trial Compass
CompletedNot Applicable
Evaluation of the Effect of Repetitive Peripheral Magnetic Stimulation on Upper Extremity Spasticity After Stroke
Turkey (Türkiye)48 participantsStarted 2022-04-01
Plain-language summary
Spasticity is a frequent problem in post-stroke patients. It can negatively affect the functional recovery of patients and impair their quality of life. The repetitive pulsed magnetic stimulation (rPMS) treatment has been shown to cause a reduction in muscle tone and improvement in activities of daily living in stroke patients. So far, the effects of rPMS on muscle tone, which is the neurophysiological component of spasticity, have been evaluated, but its effects on the biomechanical component (soft tissue stiffness) have not been demonstrated. In this study, the effects of rPMS on soft tissue stiffness as well as increased muscle tone will be evaluated with clinical and ultrasound elastography in post-stroke patients with upper extremity spasticity.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Being diagnosed with stroke according to the definition of the World Health Organization (1989)
* Being over 18 years old
* Having a stroke confirmed by Computed Tomography (CT) and Magnetic Resonance Imaging (MRI)
* Patients with spasticity between grade 1 and 3 according to the Modified Ashworth Scale (MAS) in the upper extremity arm/forearm muscle
* Wellness of the patient's general condition after stroke
Exclusion Criteria:
* Patients treated with botulinum toxin, phenol, alcohol injection for spasticity in the last 6 months
* Patients who have previously undergone antispastic surgery to the treatment area
* Patients with a change in oral antispastic drug use in the last 6 months
* Patients with fixed contractures in the elbow and wrist
* Patients with signs of acute inflammation in the treatment area
* Patients with bleeding diathesis
* Patients with implanted devices (cardiac pacemaker, cochlear implant, drug pumps)
* Patients with vascular problems such as deep vein thrombosis, phlebitis, varicose veins, arterial disease
* Patients with a history of cancer in the treatment area
* Pregnancy
* Patients with metal implants in the treatment area
* Patients with nonunion fractures at the treatment site
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.