UnknownNot Applicable

Abu Dhabi Diabetes and Obesity Study -2 Bariatric

United Arab Emirates1,200 participantsStarted 2016-04-25

Plain-language summary

Study on outcomes on bariatric surgery, particularly in terms of metabolic parameters in the UAE is scant. Also Genetic data from this population is limited and hence a study on genetic determinants of response to bariatric surgery is highly warranted. This study is expected to provide a better understanding of the causes of severe obesity in the UAE population and help us to evaluate the efficacy of Bariatric surgery in patients with genetic forms of obesity. The information generated will allow us to better advise patients regarding the risks and benefits of Bariatric Surgery as a treatment. Objective To investigate the metabolic outcomes of bariatric surgery, to study the prevalence of monogenic forms of obesity among a cohort of patients with morbid obesity who underwent bariatric surgery and to compare the outcomes of Bariatric surgery in patients with and without underlying genetic condition.

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients attending ICLDC who are planning to undergo, or who have already undergone BS for treatment of severe obesity. Exclusion Criteria: * Any malignant or chronic inflammatory disease, * Children in the absence of parental consent * Anyone who is not able to take part for reasons of significant incapacity or disability, including mental disability, preventing discussion of clinical history.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in weight

Timeframe: 3 months post BS

Change in weight

Timeframe: 6months post BS

Change in weight

Timeframe: 12months post BS

Change in weight

Timeframe: 18 months post BS

Change in weight

Timeframe: 24 months post BS

Change in weight

Timeframe: 36 months post BS

Change in resting metabolic rate

Timeframe: 3months post BS

Change in resting metabolic rate

Timeframe: 6 months post BS

Trial details

NCT IDNCT05140798

SponsorImperial College London Diabetes Centre

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-31

Contact for this trial

Alia Tikriti

aaltikriti@icldc.ae

View on ClinicalTrials.gov More Bariatric Surgery Candidate trials

Plain-language summary

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in weight

Timeframe: 3 months post BS

Change in weight

Timeframe: 6months post BS

Change in weight

Timeframe: 12months post BS

Change in weight

Timeframe: 18 months post BS

Change in weight

Timeframe: 24 months post BS

Change in weight

Timeframe: 36 months post BS

Change in resting metabolic rate

Timeframe: 3months post BS

Change in resting metabolic rate

Timeframe: 6 months post BS