Effect of Baobab Fruit on Postprandial Glycaemia in Healthy Adults (NCT05140629) | Clinical Trial Compass
CompletedNot Applicable
Effect of Baobab Fruit on Postprandial Glycaemia in Healthy Adults
Portugal31 participantsStarted 2017-01-02
Plain-language summary
Baobab fruits have been traditionally used in Africa due to its therapeutic proprieties attributed to it high polyphenol content. The aim of the study was to investigate the effect of baobab fruit on postprandial glycaemia on healthy adults and to measure its bioactive compounds and antioxidant activity. The study was conducted on 31 healthy subjects. The participants were randomly allocated in control group (oral glucose tolerance test (OGTT); n = 16) and in intervention group (OGTT followed by administration of 250 ml baobab aqueous extract (BAE); n = 15). Total phenols, proanthocyanidins, hydrolysable tannins and antioxidant activity (FRAP, DPPH, ABTS and inhibition of O2•- and NO• methods) were quantified. Repeated Measures ANOVA of mixed type and Independent samples t-test were used.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Not currently undergoing lactation or pregnancy,
* To be able to read and sign the informed consent.
* Healthy subjects and a fasting blood glucose \< 126 mg/dl
Exclusion Criteria:
* Subjects that were less than 8 or more than 10 hours fasting,
* To have symptoms and history of gastrointestinal, hepatic and cardiovascular diseases
* Baobab intolerance or allergy,
* Drug and/or supplement consumption capable of influencing plasma glucose
* Have ingested baobab, water, coffee or alcohol intake and smoked tobacco consumption within 8 hours before the intervention
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Postprandial blood glucose levels time curve
Timeframe: Before intervention and after 30, 60, 90, and 120 minutes after intervention
2
Incremental area under the curve of glucose levels
Timeframe: At 120 minutes after intervention
3
Blood glucose maximum concentrations
Timeframe: At 120 minutes after intervention
Trial details
NCT IDNCT05140629
SponsorEgas Moniz - Cooperativa de Ensino Superior, CRL