Active — Not RecruitingNot Applicable

Risk of Metabolic Adaptation After Weight Loss

United States60 participantsStarted 2022-09-10

Plain-language summary

This study aims at identifying the neurohormonal biomarkers that characterize individuals at risk of greater metabolic adaptation to weight loss, a disproportionate decline in resting metabolic rate during and after weight loss.

Who can participate

Age range18 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: BMI \> or = 30 any ethnicity Exclusion Criteria: weight \> or = 400 lbs. diabetes (type 2 or type 1) hypertension heart disease kidney disease liver disease active cancer post solid organ or bone marrow transplant HIV/AIDS pregnancy breastfeeding current smoker current recreational drug use

What they're measuring

change in measured and predicted resting metabolic rate during and after weight loss

Timeframe: 18 months

Trial details

NCT IDNCT05139420

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2031-11

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