CompletedNot Applicable

Efficacy of Er: YSGG Laser in Treatment of Peri-implantitis

Egypt3 participantsStarted 2023-08-10

Plain-language summary

This study will be carried out to evaluate the efficacy of Er: YSGG laser on oral biofilm removal from implant surface in various peri-implant defect morphology in the treatment of peri-implantitis as a primary objective. To assess the morphological changes and the biological response (biocompatibility) of implant surface after Er: YSGG laser therapy through Profilometer analysis and cell culture process to detect attachment, differentiation, and mineralization of Isolated rat Bone Marrow Mesenchymal stem cells (rBMMSCs) respectively as secondary objectives.

Who can participate

Age range25 Years – 55 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Sex: female or male. * Age: 25 - 55 years. * Medically controlled according to medical coding of review of systems (ROS) Exclusion Criteria: * Tobacco smoking for at least 6 months before the study enrollment * Participants with ill-fitting restorations in both upper first molars that affect the stability of the stent. * Participants not following oral hygiene instructions. * Participants on dental treatment during the study period. * Participants with a history of drug administration * Vulnerable group. * Participants with long-term mouthwash administration.

What they're measuring

visual inspection of the oral biofilm removal efficacy by image analysis software (Adobe Photoshop

Timeframe: 2 weeks

Trial details

NCT IDNCT05137821

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-11-01

View on ClinicalTrials.gov More Peri-Implantitis trials