UnknownNot Applicable

Ablation of Esophageal Inlet Patches in Patients Referred for Bravo pH-Testing

100 participantsStarted 2021-12

Plain-language summary

Patients with suspected extra-esophageal manifestations of gastro-esophageal reflux disease (GERD), such as cough, hoarseness, and globus, are often referred for pH testing. However, many of these symptoms may actually be due to an esophageal inlet patch. We aim to evaluate patients referred for pH testing to see if they have an inlet patch, to perform ablation of the inlet patch if detected, and then compare the outcomes of patients with an inlet patch who underwent ablation versus those without an inlet patch.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients (age 18 and above) * Referred for pH-testing for evaluation of possible extraesophageal-GERD * Prior upper endoscopy performed * Prior trial of PPI with an inadequate response Exclusion Criteria: * Patients who do not give consent * Patients with abnormalities on their prior endoscopy including a significant hiatal hernia (\>3 cm) or significant erosive esophagitis (Los Angeles class B or greater) * Patients who did not fail a prior trial of PPI therapy

What they're measuring

Symptoms 6 months after procedure

Timeframe: 6 months after procedure

Trial details

NCT IDNCT05131932

SponsorAssaf-Harofeh Medical Center

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2023-12

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