Transforaminal Epidural Platelet Rich Plasma Versus Epidural Steroid Injection for Lumbosacral Radicular Pain

Inclusion Criteria: * Age 18 years or above * average radicular leg pain of ≥ 4 (numerical rating scale (NRS) 0-10) over the past week, * Unilateral radicular leg pain * symptoms and/or signs of lumbosacral radicular pain (such as lower leg pain or back/buttock pain radiating to lower limb or positive straight leg raising or lower limb numbness or altered lower limb sensation) * pain duration more than 6 weeks * Imaging findings (magnetic resonance imaging) of a pathologic condition correlating with symptoms or signs (herniated disc or annular tear or spinal stenosis) * able to provide informed consent Exclusion Criteria: * patients require surgical intervention * coagulopathy (platelet count less than 100,000/ml, international normalized ratio \[INR\] over 1.5). * Using anticoagulant and/or antiplatelet medication (not including aspirin) * received epidural steroid injection within the past 1 year * systemic infection * previous lumbar spine surgery * allergy: contrast dye, steroids, PRP, local anaesthetic * pregnancy * physically unable to tolerate epidural injection * uncontrolled psychiatric disorder (Beck depression score ≥ 21) * active or a history of substance use disorder (including alcohol, opioid) * known secondary gain (eg active litigation) * patients with predominantly neurogenic claudication (pain over the calves, buttock, and/or thigh triggered by walking and/or prolonged standing in upright position). * back pain greater than leg pain