The metabolic alterations associated with critical illness have significant implications for the nutritional management of ICU patients. Despite this, little is known about these changes in patients requiring prolonged organ support and nutritional therapy. The overall aim of this study is to describe changes in metabolism over time in a large prospective cohort of patients requiring \>10 days of ICU care. Our hypothesis is that there is a significant change in mean energy expenditure and respiratory quotient (RQ) between the early (day 1-3), intermediate (day 4-10) and late (\>10 days) phase in ICU.
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Change in resting energy expenditure over time in patients who stay in ICU for >10 days.
Timeframe: From date of ICU admission to the date of ICU discharge or death, whichever came first, assessed up to 24 months.