Active — Not RecruitingNot Applicable

Medication Use and Quality of Life Among Older People

Denmark188 participantsStarted 2021-10-26

Plain-language summary

This project will provide new evidence on how to optimize medication use among older people with limited life expectancy. This will be done by testing whether a patient-centered deprescribing intervention, focused on aligning medical treatment with patients' preferences, can improve quality of life among older people with limited life expectancy.

Who can participate

Age range80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged ≥ 80 years * Take ≥ 8 different medications * Have a life expectancy of \<2 years, estimated via the Surprise Question ("Would you be surprised if this patient died within 1-2 years?") by the general practitioner * have a Mini-Mental State Exam (MMSE) score of ≥18 * Are able to provide informed consent Exclusion Criteria: * Not able to communicate * Does not speak and understand Danish

What they're measuring

HEALTH-RELATED QUALITY OF LIFE

Timeframe: Baseline

CHANGE FROM BASLINE HEALTH-RELATED QUALITY OF LIFE AT 3 MONTHS

Timeframe: 3 months

CHANGE FROM BASLINE HEALTH-RELATED QUALITY OF LIFE AT 6 MONTHS

Timeframe: 6 months

HEALTH-RELATED QUALITY OF LIFE (DEPRESSION)

Timeframe: Baseline

CHANGE FROM BASLINE HEALTH-RELATED QUALITY OF LIFE (DEPRESSION) AT 3 MONTHS

Timeframe: 3 months

CHANGE FROM BASLINE HEALTH-RELATED QUALITY OF LIFE (DEPRESSION) AT 6 MONTHS

Timeframe: 6 months

MORTALITY

Timeframe: 3 months

MORTALITY

Timeframe: 6 months

Trial details

NCT IDNCT05123313

SponsorOdense University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12

View on ClinicalTrials.gov More Quality of Life trials