Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial).

Inclusion Criteria: * Ability to give informed consent to the study * Age \> 18y * MINOCA diagnosis, defined as: * Acute myocardial infarction (based on Fourth Universal Definition of Myocardial Infarction Criteria): * Evidence of non-obstructive coronary artery disease on angiography (i.e., no coronary artery stenosis \>50%) in any major epicardial vessel. * No specific alternate diagnosis for the clinical presentation (i.e. non-ischemic causes of myocardial injury such as sepsis, pulmonary embolism, and myocarditis). Exclusion Criteria: * Inability or limited capacity to give informed consent to the study * Age \< 18 y * Pregnant and breast-feeding women or patients considering becoming pregnant during the study period will be excluded. For women of childbearing potential, the use of a highly effective contraceptive measure is required in order to be included in the study. "Highly effective contraceptive" is defined in accordance with the recommendations of the Clinical Trial Facilitation Group as a contraceptive measure with a failure rate of less than 1% per year (https://www.hma.eu/fileadmin/dateien/Human\_Medicines/01-About\_HMA/Working\_Groups/CTFG/2020\_09\_HMA\_CTFG\_Contraception\_guidance\_Version\_1.1\_updated.pdf). * Alternate diagnosis for the clinical presentation (i.e. non-ischemic causes of myocardial injury such as sepsis, pulmonary embolism, valve disease, hypertrophic cardiomyopathy and myocarditis). Also patients presenting with Takotsubo syndro…