CompletedNot Applicable

Common Elements Treatment Approach HIV Alcohol Reduction Trial in Zambia

Zambia680 participantsStarted 2023-01-24

Plain-language summary

This study, which is part of the Zambia Alabama HIV Alcohol Comorbidities Program funded by NIH-NIAAA, is designed to examine the efficacy of brief and in-depth cognitive behavioral therapy-based interventions to address, unhealthy alcohol use, comorbid mental health symptoms, and HIV treatment outcomes among people living with HIV in Zambia. A 3-arm trial will be conducted with participants randomized to a brief intervention alone, the brief intervention plus referral to Common Elements Treatment Approach (CETA), or standard of care (SOC).

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years of age or older * Living with HIV * Receiving HIV care at study site * Hazardous alcohol use plus at least one mental health or other substance use comorbidity or moderate to severe alcohol use disorder regardless of comorbidity * 6 months since initiation of Antiretroviral Treatment (ART) * Suboptimal HIV care outcome based on at least 1 of the following occurences in the past year: Late (at least 14 days from scheduled) Antiretroviral Treatment (ART) drug pick up, HIV viral load (VL) above the limit of assay detection, or referral to enhanced adherence Exclusion Criteria: * Plan to relocate out of Lusaka in next 6 months * No access to a telephone * Actively suicidal or alcohol intoxication and in need of immediate care * Currently psychotic * Participating in another interventional study that would interfere with participation

What they're measuring

HIV Viral Load Suppression at 6 months

Timeframe: 6 months

Trial details

NCT IDNCT05121064

SponsorUniversity of Alabama at Birmingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-31