The IMiC Consortium will analyze milk from 1000 mother-infant dyads across 4 diverse settings (Tanzania, Pakistan, Burkina Faso and Canada). Samples will be stored centrally at the Manitoba Interdisciplinary Lactation Centre (MILC) biorepository and distributed to multiple laboratories for analysis of macronutrients, micronutrients, oligosaccharides, growth factors, immunoglobulins, cytokines, metabolites and microbes. Data will be harmonized and stored in a central database, and diverse statistical methods will be applied for data integration and analysis.
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Create an international consortium of 4 birth cohorts in Tanzania, Pakistan, Burkina Faso and Canada (Field Site Partners), human milk scientists (Laboratory Partners), and data scientists and biostatisticians (Data Science Partners).
Timeframe: This outcome is anticipated to reach completion in December 2021.
Create a centralized biorepository of human milk samples from the Field Site Partners, housed at the Manitoba Interdisciplinary Lactation Centre (MILC) at the University of Manitoba in Winnipeg, Manitoba, Canada.
Timeframe: This outcome is anticipated to reach completion in April 2022.
Create a standardized protocol for the comprehensive analysis of human milk composition using state-of-the-art methods in expert laboratories
Timeframe: This outcome is anticipated to reach completion in December 2021.
Create a harmonized dataset of human milk composition and relevant maternal, infant and environmental data from 1000 dyads
Timeframe: This outcome is anticipated to reach completion in October 2023.
Create an integrated analysis of this dataset
Timeframe: This outcome is anticipated to reach completion in October 2023.