Estrogen and Platelet Rich Plasma in Treatment of Atrophic Vaginitis

Inclusion Criteria: * postmenopausal women aged 50-70 years old * with a clinical diagnosis of vaginal atrophy who will not need systemic estrogen therapy for the treatment of vasomotor symptoms or prophylaxis of osteoporosis * Any parity. Exclusion Criteria: * Women with any history of carcinoma of the breast or endometrium, * abnormal genital bleeding, acute thrombophlebitis, or thromboembolic disorders associated with previous estrogen use, * or current urinary. * In addition, women who underwent hormone replacement therapy, treated with systemic or vaginal estrogen within 6 months prior to the study, * or had any contraindication for estrogen therapy will be excluded from the study.