Not Yet RecruitingNot Applicable

Testing a Precision Psychotherapy System for Low-income Patients

111 participantsStarted 2026-02

Plain-language summary

The purpose of this study is to evaluate the feasibility of an evidence-based system to recommend core interventions, before the beginning of treatment, to psychotherapists treating low-income patients with depressive or anxiety disorders.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnoses of a depressive disorder (i.e., major depressive disorder or dysthymic disorder) or an anxiety disorder (i.e., specific phobia, social anxiety disorder, panic disorder, agoraphobia or generalized anxiety disorder) determined with the Mini-International Neuropsychiatric Interview (MINI) * A score of at least two (mild) in any the five items from the depression and anxiety domains of the DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure-Adult * A total family income below the poverty index threshold, determined by a Licensed Social Worker * Aged 18 to 65 * Fluency in Spanish language * Capacity to consent Exclusion Criteria: * Psychosis * Mania * Suicidal ideation with intent and/or plan * Substance abuse disorders * History of organic mental disease.

What they're measuring

Change from Baseline in Depressive Severity on the Patient Health Questionnaire (PHQ-9) at Week 15

Timeframe: Baseline and Week 15

Change from Baseline in Anxiety Severity on the General Anxiety Disorder-7 (GAD-7) at Week 15

Timeframe: Baseline and Week 15

Change from Baseline in Overall Functioning on the World Health Organization Disability Assessment Schedule (WHODAS) at Week 15

Timeframe: Baseline and Week 15

Average Adherence to the Recommended Interventions on the Multitheoretical List of Therapeutic Interventions (MULTI-30) Across Treatment

Timeframe: Week 1 and Week 15

Trial details

NCT IDNCT05118594

SponsorNational Council of Scientific and Technical Research, Argentina

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-11

Contact for this trial

Juan M Gomez Penedo, PhD

+5491165257053 jmgomezpenedo@gmail.com

View on ClinicalTrials.gov More Major Depressive Disorder trials

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change from Baseline in Depressive Severity on the Patient Health Questionnaire (PHQ-9) at Week 15

Timeframe: Baseline and Week 15

Change from Baseline in Anxiety Severity on the General Anxiety Disorder-7 (GAD-7) at Week 15

Timeframe: Baseline and Week 15

Change from Baseline in Overall Functioning on the World Health Organization Disability Assessment Schedule (WHODAS) at Week 15

Timeframe: Baseline and Week 15

Average Adherence to the Recommended Interventions on the Multitheoretical List of Therapeutic Interventions (MULTI-30) Across Treatment

Timeframe: Week 1 and Week 15