Hydration Dynamics and Influence of Beverage Composition (NCT05111392) | Clinical Trial Compass
CompletedPhase 1/2
Hydration Dynamics and Influence of Beverage Composition
United States14 participantsStarted 2021-09-03
Plain-language summary
The study examines interactions between fluid availability in the gut and fluid retention in the body. The relative rate of fluid uptake, the expansion of the plasma volume, and percent of fluid retained by the body will be measured in response to ingestion of beverages of different composition. Healthy, euhydrated adults will be studied. The results will help establish formulations of beverages that sustain if not promote acute euhydration.
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Have a BMI of 18.5 to 29.9 kg/m2.
* Be normotensive (\<120/80 mm Hg).
* Must be able to speak and read English.
* Be physically active or a regular exerciser but be able to abstain from exercise for 48 h prior to each study trial.
* Fast for at least 8 hours prior to and through the study trial.
* Be able to abstain from alcohol for 48 h prior to each study.
* Be able to abstain from caffeine for 24 h prior to each study.
* If female, must have regular menstrual cycles, that are \> 27 days and \< 35 days in length.
Exclusion Criteria:
* Under 18 y of age or over 45 y of age.
* Have a BMI \<18.5 or \>30.
* Being pregnant.
* Lactating.
* Tobacco user.
* Have hypotension or hypertension.
* Have any type of kidney disease or dysfunction.
* Have diabetes.
* Have any type of cardiovascular disease.
* Have been diagnosed with galactosemia.
* Females with irregular menstrual cycles.
* Females with polycystic ovary disease.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Rate of appearance of deuterium in the plasma for placebo
Timeframe: 2 hours
2
Rate of appearance of deuterium in the plasma for oral rehydration solution 1.
Timeframe: 2 hours
3
Rate of appearance of deuterium in the plasma for oral rehydration solution 2.