Exercise and Time of Day in Type 2 Diabetes (NCT05108987) | Clinical Trial Compass
CompletedNot Applicable
Exercise and Time of Day in Type 2 Diabetes
United States36 participantsStarted 2021-09-25
Plain-language summary
The overall purpose of the study is to test the effect exercise time of day in adults with type 2 diabetes or prediabetes. The overarching hypothesis is that afternoon exercise in the afternoon may promote better changes in metabolic and vascular insulin sensitivity. We anticipate that these changes will correlate with glycemic control and blood pressure changes.
Who can participate
Age range
30 Years – 80 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female \>30 and \<80 years old.
* Has a body mass index \>25 and \<45 kg/m2.
* Previously diagnosed with prediabetes and/or T2D.
* If not previously diagnosed, has a fasting blood glucose ≥ 100 mg/dL and/or HbA1c ≥ 5.7%
Exclusion Criteria:
* Morbidly obese patients (BMI \>45 kg/m2) and lean patients (BMI \<25 kg/m2)
* Evidence of type 1 diabetes and diabetics requiring insulin therapy.
* Subjects who have not been weight stable (\>2 kg weight change in past 3 months)
* Subjects who have been recently active (\>30 min of moderate/high intensity exercise, 3 times/week).
* Subjects who are smokers or who have quit smoking \<1 years ago
* Subjects with abnormal estimated glomerular filtration rate (eGFR).
* Hypertriglyceridemic (\>400 mg/dl) and hypercholesterolemic (\>260 mg/dl) subjects
* Hypertensive (\>160/100 mmHg)
* Subjects with a history of significant metabolic, cardiac, congestive heart failure, cerebrovascular, hematological, pulmonary, gastrointestinal, liver, renal, or endocrine disease or cancer that in the investigator's opinion would interfere with, alter the outcome measures, or impact subject safety.
* Pregnant (as evidenced by positive urine pregnancy test) or nursing women.
* Subjects with contraindications to participation in an exercise training program
* Currently taking active weight suppression medication (e.g. phentermine,orlistat, lorcaserin, naltrexone-bupropion in combination, liraglutide, benzphetamine, diethylpropion…
What they're measuring
1
Body Weight
Timeframe: Over the course of 2 weeks.
Trial details
NCT IDNCT05108987
SponsorRutgers, The State University of New Jersey