Active — Not RecruitingNot Applicable

Variation in Humeral Head Bone Marrow Characteristics With Rotator Cuff Repair Healing

United States50 participantsStarted 2021-11-22

Plain-language summary

This study investigates correlations between humeral head bone marrow characteristics and tendon healing of rotator cuff repairs. The anticipated results would motivate future research aimed to investigate local enrichment or transplantation of connective tissue progenitor cells to augment rotator cuff repair and the pursuit of novel methods of bone marrow screening to preoperatively identify patients with bone marrow characteristics related to rotator cuff repair success or failure.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Males or females * 18-75 years * 1-5 cm full thickness tear of the supraspinatus and/or infraspinatus tendon(s) that is fully reparable by double row technique as confirmed at surgery Exclusion Criteria: A 35 point exclusion criteria covers a variety of shoulder, musculoskeletal and general heath related conditions such as: * prior shoulder surgery (including rotator cuff repair) * symptomatic cervical spine disease * a frozen shoulder-- defined as a loss of passive range of motion (ROM) of more than 20° in any plane compared to the contralateral shoulder * advanced (grade 3 or 4) glenohumeral arthritis * worker's compensation cases * isolated subscapularis tears.

What they're measuring

Tendon healing

Timeframe: 6 months post-operation

Tendon healing

Timeframe: 6 months post-operation

Trial details

NCT IDNCT05106088

SponsorThe Cleveland Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-22

View on ClinicalTrials.gov More Rotator Cuff Tears trials