WithdrawnNot Applicable

The Longitudinal Impact of SES and the CNDS on Recovery From SUD

Stopped: proposal not funded

0Started 2025-12-01

Plain-language summary

The goal of this study is to provide a scientific understanding of the impact of socioeconomic status (SES) on the recovery trajectory (psychosocial functioning, relapse/remission status, and neurocognitive mechanisms).

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. be ≥18 yrs old
. meet lifetime DSM-5 SUD criteria
. have a Recovery Initiation Date less than 3 years prior to the time of enrollment
. be able to read independently
. be free of legal problems that could limit participation
. reside in the U.S.
. anticipate continued Internet access (to ensure ongoing contact and data collection)
. be a registrant of the International Quit and Recovery Registry (IQRR)

Exclusion criteria

. Minors will not be included
. Prisoners will not be included. If participants become incarcerated during this study, they will not be contacted to complete assessments during their incarceration. If the incarceration ends during the study, they may be contacted to participate in assessments.
. Adults who are not capable of consenting on their own behalf

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Socioeconomic Status (SES)- Individual Subjective SES

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Socioeconomic Status (SES)- Individual Objective SES

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in CNDS functioning

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Psychosocial Functioning- The Psychosocial Functioning Inventory (PFI)

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Psychosocial Functioning- World Health Organization (WHO)-Quality of Life

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Psychosocial Functioning- Satisfaction with Life and social Functioning

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Trial details

NCT IDNCT05103514

SponsorVirginia Polytechnic Institute and State University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-04-01

View on ClinicalTrials.gov More Substance Use Disorders trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. be ≥18 yrs old
. meet lifetime DSM-5 SUD criteria
. have a Recovery Initiation Date less than 3 years prior to the time of enrollment
. be able to read independently
. be free of legal problems that could limit participation
. reside in the U.S.
. anticipate continued Internet access (to ensure ongoing contact and data collection)
. be a registrant of the International Quit and Recovery Registry (IQRR)

Exclusion criteria

. Minors will not be included
. Prisoners will not be included. If participants become incarcerated during this study, they will not be contacted to complete assessments during their incarceration. If the incarceration ends during the study, they may be contacted to participate in assessments.
. Adults who are not capable of consenting on their own behalf

What they're measuring

Change in Socioeconomic Status (SES)- Individual Subjective SES

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Socioeconomic Status (SES)- Individual Objective SES

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in CNDS functioning

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Psychosocial Functioning- The Psychosocial Functioning Inventory (PFI)

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Psychosocial Functioning- World Health Organization (WHO)-Quality of Life

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years

Change in Psychosocial Functioning- Satisfaction with Life and social Functioning

Timeframe: Approximately every 3 months from date of baseline session through study completion, an average of 3 years