MyGeneMyDiet Trial for Weight Management (NCT05098899) | Clinical Trial Compass
CompletedNot Applicable
MyGeneMyDiet Trial for Weight Management
Philippines62 participantsStarted 2021-12-01
Plain-language summary
The study aims to determine if genotype-based nutrition and lifestyle advice is effective for the management of overweight and obesity among Filipino adults compared to the usual standard of care.
Who can participate
Age range19 Years – 59 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Overweight or obese Filipino adults who signify a willingness to participate in the study
* With BMI equal to 25.0 but not more than 40 kg/m2
* Apparently healthy (fasting blood glucose, lipid profile, and blood pressure within the normal range to pre-disease state)
* Normal thyroid hormone levels in the blood
* Normal blood cortisol level
* Carriers of at least one of the risk alleles of FTO rs9939609, UCP1 rs1800592, and TCF7L2 rs7903146
Exclusion Criteria:
* Elevated levels of fasting blood glucose, blood lipids, and blood pressure
* Elevated levels of thyroid hormones, and cortisol level
* Self-reported/history of heart disease
* Participation in a weight loss program or adherence to restrictive /therapeutic diet in the past 3 month
* Self-reported of recent weight changes greater or less than 3.0 kg
* Planned or recent bariatric surgery
* Consumption of weight-altering medications and/or nutritional supplements that promote weight gain/loss in the past 6 months
* Clinical diagnosis of any mental disorder and current use of any mental health medications
* Pregnant, nursing, or with self-declared intention to become pregnant
* Any health condition that may put the participant at risk
* Current and anticipated enrolment in another research study during the course of the trial
What they're measuring
1
5% weight loss
Timeframe: 24 weeks
2
10% weight loss
Timeframe: 48 weeks
3
Body mass index
Timeframe: 24 weeks
4
Waist circumference
Timeframe: 24 weeks
5
Body fat percentage
Timeframe: 24 weeks
Trial details
NCT IDNCT05098899
SponsorFood and Nutrition Research Institute, Philippines