CompletedEarly Phase 1

Effect of Atracurium and Rocuronium on the State and Response Entropy During Isoflurane Anesthesia

Egypt40 participantsStarted 2020-06-20

Plain-language summary

Many studies have explored the effects of inhalation anesthetics, intravenous anesthetics, and muscle relaxants on spectral entropy, but most did not monitor the degree of neuromuscular block. In addition, they do not explore the effects of different degrees of neuromuscular blockade on spectral entropy under different concentrations of isoflurane inhalation. Therefore, the present study will evaluate different levels of MAC to quantify the isoflurane concentration, as well as different degrees of neuromuscular blockade

Who can participate

Age range20 Years – 50 Years

SexMALE

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Inclusion criteria

✓. Patients American Society of Anesthesiologists physical status (ASA) I to II.
✓. Male patients (to avoid bias between gender).
✓. Age between 20-50 years

What they're measuring

to evaluate the impact of different degrees of neuromuscular blockade on SE, RE, and RE-SE difference during isoflurane anesthesia.

Timeframe: 1 year

Trial details

NCT IDNCT05097508

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-06-20

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