CompletedNot Applicable

Attachment and Biobehavioral Catch-up and Depression Treatment

United States76 participantsStarted 2022-03-01

Plain-language summary

Maternal depression influences the development of children's behavior problems and vice versa; however most interventions singularly address maternal depression or children's behavior problems rather than both. This project assesses the efficacy of an intervention that treats both mothers and children in an integrated manner. Effects are expected to disrupt the reciprocal relations that perpetuate maternal and child mental health problems over time.

Who can participate

Age range2 Years

SexFEMALE

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Inclusion criteria

✓. Mothers 18 years of age or older with heightened depressive symptoms as determined by a score of 5 or higher on the Patient Health Questionnaire-9 (PHQ-9)
✓. Biological children (of mothers described above) between 2 and 4 years old with heightened behavior problems as determined by a score of at least 3 in at least 1 domain of functioning on the Impairment Rating Scales
✓. English- or Spanish-speaking

Exclusion criteria

✕. Self-reported history of psychosis or active suicidality as defined by self-report of a specific suicide plan or recent attempt
✕. Child diagnosis of autism

What they're measuring

Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Score

Timeframe: Baseline to post-intervention. This is approximately 10 weeks.

Change in Early Childhood Screening Assessment (ECSA) Score

Timeframe: Baseline to post-intervention. This is approximately 10 weeks.

Trial details

NCT IDNCT05096611

SponsorUniversity of California, San Francisco

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-30

Results submitted2026-01-15

View on ClinicalTrials.gov More Maternal Depression trials