Effects of Fluid Therapy on Peripheral TIssse Perfusion During Sepsis/Septic Shock

Inclusion Criteria: * Age\> 18 years old * Sepsis or * Septic shock within 24 hours of admission to intensive care with a stable dose of norepinephrine for at least 2 hours to maintain MAP\> 65mmHg * CRT index\> 3 seconds despite the initial resuscitation (administration of antibiotics, volume expansion by crystalloids of 20 mL / Kg, noradrenaline started) between the admission to intensive care and H48 from admission to intensive care * Non-opposition of the patient collected by the doctor in charge of the patient between H0 and H6 after admission if the patient is vigilant, otherwise a procedure for collecting non-opposition from relatives will be carried out with collection of the non-opposition of the patient once he is able to give it. * Affiliation to a social security regimen (excluding AME) Exclusion Criteria: * Patient COVID-19 (+) with respiratory impairment * Pregnant and lactating woman * Patient under Guardianship / Curatorship * Refusal to participate * CRT not evaluable (dark or damaged skin) * Moribund patient * Estimated life expectancy less than 1 month * Participation in another interventional research involving the human person or period of exclusion at the end of a previous research involving the human person