Brown Adipose Tissue Metabolism in Type 2 Diabetes

Inclusion Criteria: * 10 men and 10 women with T2D. * 10 non-diabetic men and 10 non-diabetic women (matched for sex, BMI and age to the T2D participants). Exclusion Criteria: * Change in weight of more than 2 kg over the past 3 months or recent changes in lifestyle; * Treatment with a fibrate, thiazolidinedione, insulin, beta-blocker, GLP-1 agonist, or other drug known to affect lipid or carbohydrate metabolism, except statins, metformin, sulfonylurea, DPP-IV inhibitor and other antihypertensive agents that can be temporarily stopped safely prior to the studies, as per our approved protocols; * Presence of overt cardiovascular, liver, renal or other medical conditions; * Smoking or consumption of more than 2 alcoholic beverages per day; * Any other contraindication to temporarily suspending current medications for lipids or hypertension; * Any contraindication to MRI scanning. * Having participated to a research study with exposure to radiation in the last two years before the start of the study.