CompletedNot Applicable

High Velocity Nasal Insufflation (Hi-VNI) Use in Upper Airway Surgery

United States31 participantsStarted 2020-10-22

Plain-language summary

The goals of this study are to establish the efficacy of Hi-VNI (High Velocity Nasal Insufflation) in upper airway surgery from the anesthesiologist's and surgeon's perspectives, and to describe the ideal patient and the ideal pathology as well as suitable clinical scenarios when this oxygenation technique should be selected.

Who can participate

Age range

22 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Scheduled to undergo elective upper airway surgery at the University of Pennsylvania Exclusion Criteria: * Underlying medical conditions in which brief periods of hypoxemia or hypercarbia are not well tolerated * Coronary artery disease * Severe heart failure with EF \< 40% or implanted ICD * Pulmonary hypertension or pulmonary fibrosis * History of increased intracranial pressure * History of skull base or intracranial surgery * Severe nasal obstruction * Extremely low or extremely high BMI (BMI \<16 or \>40) * At high risk for aspiration * Taken to OR for urgent or emergent upper airway surgery

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Surgical Case Completion Rate Using HVNI With or Without Converting to Alternative Mode of Oxygenation

Timeframe: 1 day

Trial details

NCT IDNCT05090852

SponsorNatasha Mirza

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-09-30

Results submitted2022-07-25

View on ClinicalTrials.gov More Upper Airway Surgery trials