Paclitaxel-Coated Balloon for the Treatment of AVF

Inclusion Criteria: * Age during 18-85 years old * Arteriovenous fistula is matured and has undergone one or more hemodialysis sessions * Venous stenosis of the AV fistula * target lesion has stenosis ≥50% evidenced by angiography. and have at least one symptom of these：1,the venous pressure increased significantly during dialysis. 2,abnormal physical examination. 3,Decrease in blood flow * the length of target lesion ≤100mm * Patient able to give informed consent * residual stenosis ≤30% after predilation Exclusion Criteria: * Women who are breastfeeding, pregnant or are intending to become pregnant * AVF located at lower limbs * Two or more than two stenosis at the target vessel. * Obstruction of central venous return * ISR * AVF with acute thrombosis requiring lysis or thrombectomy in 30 days * Vascular access has surgery in 30 days or intending to undergo a surgery * Known hypersensitivity to aspirin, heparin, clopidogrel,paclitaxel, contrast medium, etc. * Patients undergoing immunotherapy or suspected / confirmed vasculitis * Patients with history of blood coagulation dysfunction and history of thrombocytopenic purpura * Vascular access infection or systemic active infection * Patients's life expectancy is less than 12 months * Renal transplantation has been planned or converted to peritoneal dialysis * Other medical conditions that lead to researchers who believe that patients may not be able to follow the trial program * Involved in other drugs, biology, medical de…