The goal is to develop methodology to monitor flux in the citric acid cycle in brain via 13C nuclear magnetic resonance (NMR) spectroscopy at 7 Tesla.
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Select metabolite abundance measured at 7Tfield strength
Timeframe: Day 1, immediately after 13 C labeled isotope infusion
Select metabolite abundance measured at 3T field strength
Timeframe: Day 1, immediately after 13 C labeled isotope infusion