CompletedNot Applicable

White Rice and Effect of Gellan Gum on Glucose Responses by MRI

United Kingdom12 participantsStarted 2021-07-14

Plain-language summary

Rice is a staple food for over half the world's population. High consumption of white rice has been linked with high obesity and increased risk for type 2 diabetes. However, it is still the favoured type of rice among consumers, contributing to the observed increasing trends in diet-related diseases in countries with high rice consumption. Controlling the properties of white rice products (e.g. reducing the glycaemic index and/or increasing satiety) with relatively simple interventions could contribute to producing foods with health-promoting digestibility profiles. One way to reduce the glycaemic index of white rice is through processing. Addition of food thickeners (called hydrocolloid gums) has previously been shown to reduce the digestibility of foods. This work will test the hypothesis that gellan gum is a simple way to manipulate the body's glucose response to a white rice which in turn will have health-promoting effects. MRI imaging will be used to monitor the gastrointestinal responses.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion Criteria: * Body mass index (BMI) ≥ 18.5 and ≤ 24.9 kg/m2 * Able to give informed consent * Apparently healthy: no medical conditions or previous gastrointestinal surgery which might affect study measurements (judged by the investigators) Exclusion Criteria: * Fasting fingerprick screening blood sugar level higher than 5.4 mmol/L * Restrained eating behaviour as determined by Eating habits and SCOFF screening questionnaires * Not used to eating breakfast * Not used to eating three meals a day * Use of medication which interferes with study measurements for example acid suppressants or anti-spasmodics. * Participation in another nutritional or biomedical trial 3 months before the pre-study screening or during the study. * Reported participation in night shift work during the two weeks prior to pre-study investigation or during the study. Night work is defined as working between midnight and 6.00 AM. * Strenuous exercise for more than10 hours per week. * Consumption of ≥21 alcoholic drinks in a typical week * Reported weight loss or gain ≥ 10 % of bodyweight during the six months period before the pre-study examination. * Following a medically- or self-prescribed diet during the two weeks prior to the pre-study examination and until the end of the study * Dislike of the products served as the dietary test treatments including the pasta meal * Any allergy or food intolerance to the test treatments * Not suitable for MRI scanning (e.g., presence of metal implants, in…

What they're measuring

Incremental Area Under the Curve of post prandial blood glucose up to 2h (iAUC2h)

Timeframe: 2 hours

Trial details

NCT IDNCT05080400

SponsorUniversity of Nottingham

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-10-27