Effect of Vitamin Supplementation in Glaucoma Patients (NCT05080153) | Clinical Trial Compass
CompletedNot Applicable
Effect of Vitamin Supplementation in Glaucoma Patients
Belgium26 participantsStarted 2019-11-15
Plain-language summary
The impact of targeted vitamin supplementation on retinal venous pressure (RVP) and steady state pattern ERG (SSpERG) in patients with RVP 15mmHg or more above intra-ocular pressure (IOP) and serum homocystein 12µmol/l or more, with signs of progression in spite of adequate IOP control, as evidenced by SSpERG abnormality with or without structural progression or visual field progression,
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* glaucoma and/or ocular vascular disease in at least on eye
* abnormal SSpERG
* RVP measured using an ophthalmodynamometer at least 15 mmHg higher than intra-ocular pressure (IOP),
* fasting serum Hcy level \> 12 µmol/l
* stable and well-controlled IOP (with or without IOP-lowering treatment)
Exclusion Criteria:
* starting other systemic or ocular medications with potential impacts on RVP within a month before entering the study or during the course of the study
* starting or changing the dosage of other medications with potential impact on SSpERG within 3 months before entering the study or during the course of the study
* non-adherence to the follow-up schedule
* inability to perform a proper RVP measurement using ophthalmodynamometry.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.