Acute Kidney Injury After Cardiac Surgery (NCT05079724) | Clinical Trial Compass
UnknownNot Applicable
Acute Kidney Injury After Cardiac Surgery
200 participantsStarted 2021-11-01
Plain-language summary
The study aims to identify the Following: -
1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes).
2. use of biomarkers for the early detection of clinical and subclinical cardiac Surgery associated-AKI.
3. risk factors and prediction models of cardiac Surgery associated-AKI.
4. optimal cardiac surgical procedures including conventional versus minimally invasive approaches, on-pump versus off-pump, and optimal management of cardiac surgical support including duration of CPB, perfusion pressure, hemodilution, and hypothermia during CPB.
5. controversial pharmacologic therapies for the prevention and treatment of cardiac Surgery associated-AKI including statins, sodium bicarbonate, and N-acetylcysteine (NAC).
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* On-pump cardiac surgery;
* Off-pump Cardiac Surgery;
* Informed and written consent of the patient or inclusion according to the emergency procedure;
* Affiliated patient or beneficiary of a social protection.
Exclusion Criteria:
* Patients who underwent cardiac surgery for congenital heart disease.
* Patients who underwent emergency heart surgery.
* patients who, within the last 72 hours before surgery, were injected with iodinated contrast (because of its potential nephrotoxicity).
* patients with chronic Kidney disease. 5- patients with a preoperative serum creatinine \>2 mg/dL.
* patients who died within the first 24 hours after surgery.
* patients on mechanical ventilation before intervention.
* Patients with preoperative medical disorders other than cardiac affection.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial is focused on early identification of kidney injury risk after cardiac surgery rather than testing a new treatment, what would actually happen to me if I enrolled — would it change my care in any way, or is it purely observational?
2Given that this trial covers a wide range of cardiac conditions including valve disease, coronary bypass, and heart shock, how would my specific diagnosis affect whether this study is even relevant to my situation?
3The trial's recruitment status is listed as unknown — can you find out whether this study is still actively enrolling patients, and if not, are there similar studies looking at kidney complications after cardiac surgery that I could consider?
4If the goal is to catch kidney injury earlier after surgery, would participating in this trial mean I'd receive more frequent kidney function monitoring than I would get with standard post-surgical care, and is that something worth pursuing regardless of the trial?
5Since acute kidney injury after cardiac surgery is a known risk, what are the current standard-of-care approaches my surgical team already uses to protect my kidneys, and would this trial add anything meaningful on top of that?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The early identification of patients at risk of developing AKI after cardiac surgery