Effect of Extubation on Respiratory Function (NCT05077605) | Clinical Trial Compass
CompletedNot Applicable
Effect of Extubation on Respiratory Function
France34 participantsStarted 2021-11-05
Plain-language summary
The extubation phase is a risky period of anesthesia management. During this step, serious complications can arise: hypoxemia, laryngospasm, pharyngeal obstruction, pneumonia… In spite of these complications, extubation and its impact on respiratory function, particularly on the Functional Residual Capacity (FRC), remains poorly studied because of the difficulty to make bedside measurements.
The PulmoVista 500 is a clinical routine which provide effective non-invasive bedside measurements. It would be interesting to evaluate the impact of extubation on respiratory function, and more specifically FRC changes during and after extubation.
This study will allow a better physiopathological knowledge and a quality improvement patient extubation management.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient over 18 years
* Patient in operating room for scheduled surgery
* Patient receiving general anaesthesia with orotracheal intubation
* Patient given written consent after information
* Patient covered by social security or equivalent regimen
Exclusion Criteria:
* Patient undergoing thoracic and spinal surgery, due to the presence of dressings that interfere with measurements,
* Patient who has undergone intracerebral surgery because of possible communication difficulties upon awakening,
* Patients with a body mass index (BMI) \> 50 (measurements not possible)
* Pregnant or breastfeeding patient,
* Patient contraindicated to the use of a thoracic electroimpedancemetry technique: dressings, wounds, presence of a pacemaker, defibrillator or any other active implant.
* Patient deprived of liberty by a judicial or administrative decision or patient subject to a legal protection measure (guardianship, curatorship...)
* Patient in a period of exclusion from another research protocol
* Any other reason that, in the opinion of the investigator, could interfere with the evaluation of study objectives
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
End Expiratory Lung Impedance (EELI)
Timeframe: Between 2 and 3 hours
Trial details
NCT IDNCT05077605
SponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur Mer