A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Ane… (NCT05077111) | Clinical Trial Compass
UnknownPhase 4
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Egypt40 participantsStarted 2020-01-15
Plain-language summary
Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including avoidance of airway trauma and ventilator dependence associated with endotracheal intubation, besides promoting enhanced recovery after surgery and shorter mean hospital stay.
Who can participate
Age range
21 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ASA less than or equal II.
* The procedure expected to be completed within 2 hours.
Exclusion Criteria:
* Patients with expected difficult airway management.
* Hemodynamically unstable patients.
* Persistent cough or high airway secretions.
* Severe Emphysema or clinical signs of active infectious disease.
* Hypoxemia (PaO2 \<60 mmHg) or hypercarbia (PCO2 \>50 mmHg)
* Coagulopathy (INR \>1.5).
* Obesity (BMI \>30 Kg/m 2 ).
* Infection at the injection site, allergy to local anesthetics.
* Neurological disorders: seizures, intracranial mass or brain edema.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compares regional anesthesia to general anesthesia for thoracoscopy — given my specific condition, whether it's a pleural effusion or something else on that list, which type of anesthesia would my doctor currently recommend for me, and how does that compare to what this trial is testing?
2Since this is a Phase 4 trial, meaning the interventions being compared are already approved and used in practice, does that change how much we already know about the safety of regional versus general anesthesia for this kind of procedure, and are there still meaningful unknowns my doctor would want me to understand?
3The trial is measuring changes in blood oxygen and carbon dioxide levels around the time of surgery — what would it mean for me personally if those blood gas readings shifted significantly, and is that something my doctor already monitors closely during thoracoscopy regardless of this trial?
4The recruitment status for this trial is listed as unknown, so before I get my hopes up, can my doctor help me find out whether this study is still actively enrolling patients and where it's being conducted?
5Considering that thoracoscopy under regional anesthesia means I might be awake or only lightly sedated during the procedure, is that something my doctor thinks would be realistic for me to handle given my current health and anxiety levels, or would general anesthesia be a safer choice for my situation?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Perioperative changes in blood gases
Timeframe: Imediately before operation, intraoperatively per hour, and postoperatively till 24 hours